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matlab-based algorithm sarctrack  (MathWorks Inc)


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    MathWorks Inc matlab-based algorithm sarctrack
    Panel A. GFP-tagged α-actinin hiPSC-CMs cultured on 5 kPa PDMS (left) and <t>SarcTrack</t> wavelet fitting (right). Panel B. The relaxation of WT (black, n=9) and R278C +/− (red, n=12) hiPSC-CMs cultured on 5 kPa PDMS, with respect to: B1) time-to-half maximal relaxation (ms). B2) the maximum velocity of relaxation (μm . s −1 ). Panel C. The contractile parameters of WT (black, n=9) and R278C +/− (red, n=12) hiPSC-CMs cultured on 5 kPa PDMS and stimulated at 1 Hz with respect to: C1) percent maximal shortening; C2) time to half maximal contraction; C3) maximum velocity of contraction (μm s −1 ). (* p-value< 0.05, ** p-value <0.005, ***p-value<0.0005)
    Matlab Based Algorithm Sarctrack, supplied by MathWorks Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/matlab-based algorithm sarctrack/product/MathWorks Inc
    Average 90 stars, based on 1 article reviews
    matlab-based algorithm sarctrack - by Bioz Stars, 2026-03
    90/100 stars

    Images

    1) Product Images from "Mechanisms of Pathogenicity of Hypertrophic Cardiomyopathy-Associated Troponin T (TNNT2) Variant R278C +/− During Development"

    Article Title: Mechanisms of Pathogenicity of Hypertrophic Cardiomyopathy-Associated Troponin T (TNNT2) Variant R278C +/− During Development

    Journal: bioRxiv

    doi: 10.1101/2023.06.06.542948

    Panel A. GFP-tagged α-actinin hiPSC-CMs cultured on 5 kPa PDMS (left) and SarcTrack wavelet fitting (right). Panel B. The relaxation of WT (black, n=9) and R278C +/− (red, n=12) hiPSC-CMs cultured on 5 kPa PDMS, with respect to: B1) time-to-half maximal relaxation (ms). B2) the maximum velocity of relaxation (μm . s −1 ). Panel C. The contractile parameters of WT (black, n=9) and R278C +/− (red, n=12) hiPSC-CMs cultured on 5 kPa PDMS and stimulated at 1 Hz with respect to: C1) percent maximal shortening; C2) time to half maximal contraction; C3) maximum velocity of contraction (μm s −1 ). (* p-value< 0.05, ** p-value <0.005, ***p-value<0.0005)
    Figure Legend Snippet: Panel A. GFP-tagged α-actinin hiPSC-CMs cultured on 5 kPa PDMS (left) and SarcTrack wavelet fitting (right). Panel B. The relaxation of WT (black, n=9) and R278C +/− (red, n=12) hiPSC-CMs cultured on 5 kPa PDMS, with respect to: B1) time-to-half maximal relaxation (ms). B2) the maximum velocity of relaxation (μm . s −1 ). Panel C. The contractile parameters of WT (black, n=9) and R278C +/− (red, n=12) hiPSC-CMs cultured on 5 kPa PDMS and stimulated at 1 Hz with respect to: C1) percent maximal shortening; C2) time to half maximal contraction; C3) maximum velocity of contraction (μm s −1 ). (* p-value< 0.05, ** p-value <0.005, ***p-value<0.0005)

    Techniques Used: Cell Culture



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    matlab-based algorithm sarctrack  (MathWorks Inc)
    90
    MathWorks Inc matlab-based algorithm sarctrack
    Panel A. GFP-tagged α-actinin hiPSC-CMs cultured on 5 kPa PDMS (left) and <t>SarcTrack</t> wavelet fitting (right). Panel B. The relaxation of WT (black, n=9) and R278C +/− (red, n=12) hiPSC-CMs cultured on 5 kPa PDMS, with respect to: B1) time-to-half maximal relaxation (ms). B2) the maximum velocity of relaxation (μm . s −1 ). Panel C. The contractile parameters of WT (black, n=9) and R278C +/− (red, n=12) hiPSC-CMs cultured on 5 kPa PDMS and stimulated at 1 Hz with respect to: C1) percent maximal shortening; C2) time to half maximal contraction; C3) maximum velocity of contraction (μm s −1 ). (* p-value< 0.05, ** p-value <0.005, ***p-value<0.0005)
    Matlab Based Algorithm Sarctrack, supplied by MathWorks Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/matlab-based algorithm sarctrack/product/MathWorks Inc
    Average 90 stars, based on 1 article reviews
    matlab-based algorithm sarctrack - by Bioz Stars, 2026-03
    90/100 stars
    		  Buy from Supplier
    based algorithm sarctrack  (MathWorks Inc)
    90
    MathWorks Inc based algorithm sarctrack
    Panel A. GFP-tagged α-actinin hiPSC-CMs cultured on 5 kPa PDMS (left) and <t>SarcTrack</t> wavelet fitting (right). Panel B. The relaxation of WT (black, n=9) and R278C +/− (red, n=12) hiPSC-CMs cultured on 5 kPa PDMS, with respect to: B1) time-to-half maximal relaxation (ms). B2) the maximum velocity of relaxation (μm . s −1 ). Panel C. The contractile parameters of WT (black, n=9) and R278C +/− (red, n=12) hiPSC-CMs cultured on 5 kPa PDMS and stimulated at 1 Hz with respect to: C1) percent maximal shortening; C2) time to half maximal contraction; C3) maximum velocity of contraction (μm s −1 ). (* p-value< 0.05, ** p-value <0.005, ***p-value<0.0005)
    Based Algorithm Sarctrack, supplied by MathWorks Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/based algorithm sarctrack/product/MathWorks Inc
    Average 90 stars, based on 1 article reviews
    based algorithm sarctrack - by Bioz Stars, 2026-03
    90/100 stars
    		  Buy from Supplier
    based software algorithm sarctrack  (MathWorks Inc)
    90
    MathWorks Inc based software algorithm sarctrack
    Panel A. GFP-tagged α-actinin hiPSC-CMs cultured on 5 kPa PDMS (left) and <t>SarcTrack</t> wavelet fitting (right). Panel B. The relaxation of WT (black, n=9) and R278C +/− (red, n=12) hiPSC-CMs cultured on 5 kPa PDMS, with respect to: B1) time-to-half maximal relaxation (ms). B2) the maximum velocity of relaxation (μm . s −1 ). Panel C. The contractile parameters of WT (black, n=9) and R278C +/− (red, n=12) hiPSC-CMs cultured on 5 kPa PDMS and stimulated at 1 Hz with respect to: C1) percent maximal shortening; C2) time to half maximal contraction; C3) maximum velocity of contraction (μm s −1 ). (* p-value< 0.05, ** p-value <0.005, ***p-value<0.0005)
    Based Software Algorithm Sarctrack, supplied by MathWorks Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/based software algorithm sarctrack/product/MathWorks Inc
    Average 90 stars, based on 1 article reviews
    based software algorithm sarctrack - by Bioz Stars, 2026-03
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    Panel A. GFP-tagged α-actinin hiPSC-CMs cultured on 5 kPa PDMS (left) and SarcTrack wavelet fitting (right). Panel B. The relaxation of WT (black, n=9) and R278C +/− (red, n=12) hiPSC-CMs cultured on 5 kPa PDMS, with respect to: B1) time-to-half maximal relaxation (ms). B2) the maximum velocity of relaxation (μm . s −1 ). Panel C. The contractile parameters of WT (black, n=9) and R278C +/− (red, n=12) hiPSC-CMs cultured on 5 kPa PDMS and stimulated at 1 Hz with respect to: C1) percent maximal shortening; C2) time to half maximal contraction; C3) maximum velocity of contraction (μm s −1 ). (* p-value< 0.05, ** p-value <0.005, ***p-value<0.0005)

    Journal: bioRxiv

    Article Title: Mechanisms of Pathogenicity of Hypertrophic Cardiomyopathy-Associated Troponin T (TNNT2) Variant R278C +/− During Development

    doi: 10.1101/2023.06.06.542948

    Figure Lengend Snippet: Panel A. GFP-tagged α-actinin hiPSC-CMs cultured on 5 kPa PDMS (left) and SarcTrack wavelet fitting (right). Panel B. The relaxation of WT (black, n=9) and R278C +/− (red, n=12) hiPSC-CMs cultured on 5 kPa PDMS, with respect to: B1) time-to-half maximal relaxation (ms). B2) the maximum velocity of relaxation (μm . s −1 ). Panel C. The contractile parameters of WT (black, n=9) and R278C +/− (red, n=12) hiPSC-CMs cultured on 5 kPa PDMS and stimulated at 1 Hz with respect to: C1) percent maximal shortening; C2) time to half maximal contraction; C3) maximum velocity of contraction (μm s −1 ). (* p-value< 0.05, ** p-value <0.005, ***p-value<0.0005)

    Article Snippet: To examine the contractile properties of R278C, we employed the newly developed Matlab-based algorithm, SarcTrack, to quantify sarcomeric shortening in α-actinin 2-GFP tagged hiPSC-CMs.

    Techniques: Cell Culture

    Panel A. GFP-tagged α-actinin hiPSC-CMs cultured on 5 kPa PDMS (left) and SarcTrack wavelet fitting (right). Panel B. The relaxation of WT (black, n=9) and R278C +/− (red, n=12) hiPSC-CMs cultured on 5 kPa PDMS, with respect to: B1) time-to-half maximal relaxation (ms). B2) the maximum velocity of relaxation (μm . s −1 ). Panel C. The contractile parameters of WT (black, n=9) and R278C +/− (red, n=12) hiPSC-CMs cultured on 5 kPa PDMS and stimulated at 1 Hz with respect to: C1) percent maximal shortening; C2) time to half maximal contraction; C3) maximum velocity of contraction (μm s −1 ). (* p-value< 0.05, ** p-value <0.005, ***p-value<0.0005)

    Journal: bioRxiv

    Article Title: Mechanisms of Pathogenicity of Hypertrophic Cardiomyopathy-Associated Troponin T (TNNT2) Variant R278C +/− During Development

    doi: 10.1101/2023.06.06.542948

    Figure Lengend Snippet: Panel A. GFP-tagged α-actinin hiPSC-CMs cultured on 5 kPa PDMS (left) and SarcTrack wavelet fitting (right). Panel B. The relaxation of WT (black, n=9) and R278C +/− (red, n=12) hiPSC-CMs cultured on 5 kPa PDMS, with respect to: B1) time-to-half maximal relaxation (ms). B2) the maximum velocity of relaxation (μm . s −1 ). Panel C. The contractile parameters of WT (black, n=9) and R278C +/− (red, n=12) hiPSC-CMs cultured on 5 kPa PDMS and stimulated at 1 Hz with respect to: C1) percent maximal shortening; C2) time to half maximal contraction; C3) maximum velocity of contraction (μm s −1 ). (* p-value< 0.05, ** p-value <0.005, ***p-value<0.0005)

    Article Snippet: Using the MATLAB based algorithm SarcTrack , we found sarcomere shortening, contraction, and relaxation kinetics to be disrupted in R278C +/− hiPSC-CMs, which were alleviated in part by mavacamten.

    Techniques: Cell Culture